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T74798 |
Antipsychotic agent-2
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Antipsychotic agent-2 (Compound 11) is a potent antipsychotic with high affinities for 5-HT 1A, 5-HT 2A, 5-HT 2C, D 2, and H 1 receptors, exhibiting K i values of 56.6, 66.7, 552, 596, and 1140 nM, respectively. It also ... |
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T0031L2 |
Ziprasidone
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Geodon,Zeldox,CP-88059 |
Dopamine Receptor
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5-HT Receptor
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Adrenergic Receptor
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Norepinephrine
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Histamine Receptor
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Ziprasidone (Geodon) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity. |
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T0031 |
Ziprasidone hydrochloride monohydrate
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CP 88059 |
Dopamine Receptor
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5-HT Receptor
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Adrenergic Receptor
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Norepinephrine
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Histamine Receptor
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Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity. |
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T10232 |
Acetophenazine dimaleate
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Dopamine Receptor
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Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor. |
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T1539 |
Iloperidone
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HP 873 |
Dopamine Receptor
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5-HT Receptor
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Adrenergic Receptor
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Iloperidone (HP 873) is an atypical antipsychotic agent that is used for treatment of schizophrenia. |
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T19680 |
Zotepine
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Dopamine Receptor
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5-HT Receptor
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Adrenergic Receptor
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Histamine Receptor
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Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively. Zotepine is a second... |
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T25487 |
Haloperidol decanoate
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KD 16,KD-136,KD 136,Neoperidole,Haldol |
Others
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Haloperidol decanoate (KD 16) is a typical antipsychotic agent utilized as maintenance treatment for schizophrenia and mood disorders formulated as an ester for intramuscular injection. |
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T0351 |
Risperidone
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Risperidal,R 64 766 |
Dopamine Receptor
,
5-HT Receptor
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Adrenergic Receptor
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P-gp
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Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent. |
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T8136 |
Perospirone hydrochloride
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Perospirone HCl,SM-9018 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
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Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist. |
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T12899L |
SEP-363856 hydrochloride
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SEP-856 hydrochloride |
Others
,
5-HT Receptor
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SEP-363856 hydrochloride (SEP-856 hydrochloride) is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects, has the potential to trea... |
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T1566 |
Aripiprazole
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OPC-14597 |
5-HT Receptor
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Aripiprazole (OPC-14597) is an antipsychotic agent that is structurally related to piperazines and quinolones. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a... |
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T23733 |
Amperozide
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FG 5606,Amperozida,Amperozidum |
5-HT Receptor
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Amperozide (FG 5606) is a diphenylbutylpiperazine atypical antipsychotic which antagonizes 5-HT2A receptors. It inhibits dopamine release and alters the firing of dopaminergic neurons. Investigations regarding the use of... |
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T1735 |
Lurasidone hydrochloride
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Lurasidone HCl,SM-13496 (Hydrochloride),SM-13496 |
Dopamine Receptor
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5-HT Receptor
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Norepinephrine
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Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, serotonin 5-HT7 receptor antag... |
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T1951 |
Asenapine Maleate
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Org 5222 maleate,Org 5222 |
5-HT Receptor
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Asenapine Maleate (Org 5222 maleate) is a second generation (atypical) antipsychotic agent that is taken sublingually and used in the treatment of schizophrenia and manic or mixed episodes associated with bipolar 1 disor... |
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T2546 |
Pimozide
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R6238 |
Potassium Channel
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Dopamine Receptor
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Adrenergic Receptor
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STAT
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Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), thereby... |
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T0455 |
Clozapine
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HF 1854,LX 100-129 |
Dopamine Receptor
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Adrenergic Receptor
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AChR
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Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a... |
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T25432 |
Fluspiperone
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NSC 354855,NSC354855,NSC-354855,R-28930,R 28930 |
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Fluspiperone is an antipsychotic agent. |
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T31830 |
Flutroline
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CP-36,584,Flutrolinum,CP36,584,Flutrolino |
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Flutroline is a gamma-carboline antipsychotic agent. |
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T28514 |
Remoxipride
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Remoxipride is an antipsychotic agent. Remoxipride is specific for dopamine D2 receptors. |
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T10290 |
Alpertine
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Win 31665 |
Others
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Alpertine is an antipsychotic agent. |
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T24399 |
Lenperone HCl
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Lenperone HCl is a dopamine antagonist and an antipsychotic agent. |
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T29004 |
Trebenzomine
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Trebenzomine is apsychotropic agent with potential as an antidepressant and an antipsychotic. |
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T30753 |
Carphenazine Dimaleate
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Procethazine dimaleate,Proketazine maleate,Proketazine,carphenazine maleate,Proketazine dimaleate |
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Carphenazine is used for the treatment of chronic schizophrenia, which is an antipsychotic agent. |
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T28719 |
Sch 40853
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Sch-40853,Sch40853 |
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Sch 40853 is an active metabolite of a benzonaphthazepine antipsychotic agent. |
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T0068L |
Fluphenazine Decanoate Dihydrochloride
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Fluphenazine Decanoate Dihydrochloride is an antipsychotic agent, it could block postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia. |
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T25181 |
Bromperidol decanoate
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R46541,R-46541,R 46541 |
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Bromperidol decanoate is an antipsychotic agent that is utilized for long-term maintenance treatment for schizophrenia. |
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T70263 |
U 101958
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U 101958 is a putative antipsychotic agent It is also a highly selective dopamine D4 receptor antagonist. |
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T11753 |
Keto Ziprasidone
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Potassium Channel
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Ziprasidone, an antipsychotic agent, functions as a dual antagonist of 5-HT (serotonin) and dopamine receptors. Keto Ziprasidone represents an impurity found within Ziprasidone. |
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T11586 |
Hydroxy ziprasidone
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Others
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Hydroxy ziprasidone is an impurity of Ziprasidone. Ziprasidone, an antipsychotic agent, is a 5-HT and dopamine receptor antagonist. |
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T60944 |
(±)-Levomepromazine
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(±)-Levomepromazine is the Levomepromazine racemate. Levomepromazine is an orally active and typical antipsychotic agent [1]. |
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T15026 |
Cyamemazine
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5-HT Receptor
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Cyamemazine, contains the phenothiazine chromophore, is a neuroleptic agent used as an anxiolytic. Cyamemazine is a potent 5-HT3 (Ki: 12 nM), 5-HT2A (Ki: 1.5 nM) and 5-HT2C (Ki: 75 nM) receptors antagonist with antipsych... |
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T21669 |
Haloperidol hydrochloride
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Haloperidol hydrochloride is a potent dopamine D2 receptor antagonist which is a potent antipsychotic agent. |
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T10681 |
Cariprazine D6
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RGH-188 D6 |
Dopamine Receptor
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Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM). |
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T63592 |
Thiothixene hydrochloride
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Thiothixene hydrochloride is an antipsychotic agent that can be used in the study of schizophrenia and bipolar mania. |
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T62840 |
Bromperidol hydrochloride
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Bromperidol hydrochloride (R-11333 hydrochloride) is an antipsychotic agent with good affinity for the central dopamine receptors D2. Spectinomycin synergistically kills mycobacteria. |
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T28845 |
SR142948A HCl
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SR142948A,SR 142948A,SR-142948A,SR142948A hydrochloride |
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SR 142948A is a non-peptide antagonist of neurotensin receptor. SR 142948A affects the expression of c-Fos and has properties of antipsychotic agent. SR 142948A blocks hypothermia and analgesia induced by neurotensin. It... |
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T12899 |
SEP-363856
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SEP-856 |
Others
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SEP-363856 is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects, has the potential to treatment of schizophrenia. |
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T69129 |
Clozapine HCl
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Clozapine HCl is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serot... |
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T22044 |
BGC 20-761
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BGC20-761 is a selecvtive 5-HT6 and dopamine receptor antagonist (human receptor K i values: 5-HT6 (20 nM), 5-HT2A (69 nM), D2 (140 nM). BGC20-761 is a tryptamine analog with a high affinity for 5-HT(6) receptors, that c... |
